Detection of rpoB Mutations Associated with Rifampin Resistance in Mycobacterium tuberculosis Using Denaturing Gradient Gel Electrophoresis

Denaturing gradient gel electrophoresis (DGGE) was used to probe for mutations associated with rifampin (RIF) resistance in the rpoB gene of Mycobacterium tuberculosis. DGGE scans for mutations across large regions of DNA and is comparable to DNA sequencing in detecting DNA alterations. Specific mut...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: McCammon, Mark T., Gillette, John S., Thomas, Derek P., Ramaswamy, Srinivas V., Graviss, Edward A., Kreiswirth, Barry N., Vijg, Jan, Quitugua, Teresa N.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2005
विषय:
Mechanisms of Resistance
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140537/
https://ncbi.nlm.nih.gov/pubmed/15917513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.6.2200-2209.2005
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