Detection of rpoB Mutations Associated with Rifampin Resistance in Mycobacterium tuberculosis Using Denaturing Gradient Gel Electrophoresis

Denaturing gradient gel electrophoresis (DGGE) was used to probe for mutations associated with rifampin (RIF) resistance in the rpoB gene of Mycobacterium tuberculosis. DGGE scans for mutations across large regions of DNA and is comparable to DNA sequencing in detecting DNA alterations. Specific mut...

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Bibliografische gegevens
Hoofdauteurs: McCammon, Mark T., Gillette, John S., Thomas, Derek P., Ramaswamy, Srinivas V., Graviss, Edward A., Kreiswirth, Barry N., Vijg, Jan, Quitugua, Teresa N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
Onderwerpen:
Mechanisms of Resistance
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140537/
https://ncbi.nlm.nih.gov/pubmed/15917513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.6.2200-2209.2005
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