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Molecular Genetic Analysis of Nucleotide Polymorphisms Associated with Ethambutol Resistance in Human Isolates of Mycobacterium tuberculosis

Ethambutol (EMB) is a central component of drug regimens used worldwide for the treatment of tuberculosis. To gain insight into the molecular genetic basis of EMB resistance, approximately 2 Mb of five chromosomal regions with 12 genes in 75 epidemiologically unassociated EMB-resistant and 33 EMB-su...

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Autors principals: Ramaswamy, Srinivas V., Amin, Amol G., Göksel, Servet, Stager, Charles E., Dou, Shu-Jun, El Sahly, Hana, Moghazeh, Soraya L., Kreiswirth, Barry N., Musser, James M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC89679/
https://ncbi.nlm.nih.gov/pubmed/10639358
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