MexXY-OprM Efflux Pump Is Necessary for Adaptive Resistance of Pseudomonas aeruginosa to Aminoglycosides

Exposure of Pseudomonas aeruginosa to aminoglycosides frequently selects for recalcitrant subpopulations exhibiting an unstable, “adaptive” resistance to these antibiotics. In this study, we investigated the implication in the phenomenon of MexXY-OprM, an active efflux system known to export aminogl...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Hocquet, Didier, Vogne, Christelle, El Garch, Farid, Vejux, Anne, Gotoh, Naomasa, Lee, Angela, Lomovskaya, Olga, Plésiat, Patrick
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2003
Témata:	Mechanisms of Resistance
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152483/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12654672/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.4.1371-1375.2003
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