MexXY-OprM Efflux Pump Is Necessary for Adaptive Resistance of Pseudomonas aeruginosa to Aminoglycosides

Exposure of Pseudomonas aeruginosa to aminoglycosides frequently selects for recalcitrant subpopulations exhibiting an unstable, “adaptive” resistance to these antibiotics. In this study, we investigated the implication in the phenomenon of MexXY-OprM, an active efflux system known to export aminogl...

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Bibliografiska uppgifter
Huvudupphovsmän: Hocquet, Didier, Vogne, Christelle, El Garch, Farid, Vejux, Anne, Gotoh, Naomasa, Lee, Angela, Lomovskaya, Olga, Plésiat, Patrick
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2003
Ämnen:
Mechanisms of Resistance
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC152483/
https://ncbi.nlm.nih.gov/pubmed/12654672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.4.1371-1375.2003
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