Chargement en cours...
Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock
Mice deficient in the circadian transcription factor BMAL1 (brain and muscle ARNT-like protein) have impaired circadian behavior and demonstrate loss of rhythmicity in the expression of target genes. Here we report that Bmal1(−/−) mice have reduced lifespans and display various symptoms of premature...
Enregistré dans:
| Auteurs principaux: | , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2006
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1522083/ https://ncbi.nlm.nih.gov/pubmed/16847346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1432206 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|