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CXCR4 utilization is sufficient to trigger CD4+ T cell depletion in HIV-1-infected human lymphoid tissue

The human chemokine receptors CCR5 and CXCR4 have emerged as the predominant cofactors, along with CD4, for cellular entry of HIV-1 in vivo whereas the contribution of other chemokine receptors to HIV disease has not been yet determined. CCR5-specific (R5) viruses predominate during primary HIV-1 in...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Proc Natl Acad Sci U S A
Ngā kaituhi matua: Penn, Michael L., Grivel, Jean-Charles, Schramm, Birgit, Goldsmith, Mark A., Margolis, Leonid
Hōputu: Artigo
Reo:Inglês
I whakaputaina: National Academy of Sciences 1999
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15193/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9892690/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.2.663
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