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CXCR4 utilization is sufficient to trigger CD4+ T cell depletion in HIV-1-infected human lymphoid tissue

The human chemokine receptors CCR5 and CXCR4 have emerged as the predominant cofactors, along with CD4, for cellular entry of HIV-1 in vivo whereas the contribution of other chemokine receptors to HIV disease has not been yet determined. CCR5-specific (R5) viruses predominate during primary HIV-1 in...

詳細記述

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書誌詳細
主要な著者: Penn, Michael L., Grivel, Jean-Charles, Schramm, Birgit, Goldsmith, Mark A., Margolis, Leonid
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC15193/
https://ncbi.nlm.nih.gov/pubmed/9892690
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