Noninfectious X4 but Not R5 Human Immunodeficiency Virus Type 1 Virions Inhibit Humoral Immune Responses in Human Lymphoid Tissue Ex Vivo

Ex vivo human immunodeficiency virus type 1 (HIV-1) infection of human lymphoid tissue recapitulates some aspects of in vivo HIV-1 infection, including a severe depletion of CD4(+) T cells and suppression of humoral immune responses to recall antigens or to polyclonal stimuli. These effects are indu...

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Detalhes bibliográficos
Main Authors: Fitzgerald, Wendy, Sylwester, Andrew W., Grivel, Jean-Charles, Lifson, Jeffrey D., Margolis, Leonid B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC421649/
https://ncbi.nlm.nih.gov/pubmed/15194782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.13.7061-7068.2004
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