Interferons, Interferon Inducers, and Interferon-Ribavirin in Treatment of Flavivirus-Induced Encephalitis in Mice

We evaluated the prophylactic and therapeutic efficacy of interferon α-2b, pegylated interferon α-2b, poly(I · C), and Ampligen against Modoc virus encephalitis in an animal model for flavivirus infections. All compounds significantly delayed virus-induced morbidity (paralysis) and mortality (due to...

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Bibliographic Details
Main Authors: Leyssen, Pieter, Drosten, Christian, Paning, Marcus, Charlier, Nathalie, Paeshuyse, Jan, De Clercq, Erik, Neyts, Johan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC151739/
https://ncbi.nlm.nih.gov/pubmed/12543691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.2.777-782.2003
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