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Ribavirin Antagonizes the In Vitro Anti-Hepatitis C Virus Activity of 2′-C-Methylcytidine, the Active Component of Valopicitabine

Ribavirin antagonizes the in vitro anti-hepatitis C virus (HCV) activity of the pyrimidine nucleoside analogue 2′-C-methylcytidine, the active component of the experimental anti-HCV drug valopicitabine. In contrast, the combination of ribavirin with either the purine nucleoside analogue 2′-C-methyla...

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Detalhes bibliográficos
Main Authors: Coelmont, Lotte, Paeshuyse, Jan, Windisch, Marc P., De Clercq, Erik, Bartenschlager, Ralf, Neyts, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1610077/
https://ncbi.nlm.nih.gov/pubmed/17005827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00372-06
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