Exchanging the Yellow Fever Virus Envelope Proteins with Modoc Virus prM and E Proteins Results in a Chimeric Virus That Is Neuroinvasive in SCID Mice

A chimeric flavivirus infectious cDNA was constructed by exchanging the premembrane (prM) and envelope (E) genes of the yellow fever virus vaccine strain 17D (YF17D) with the corresponding genes of Modoc virus (MOD). This latter virus belongs to the cluster of the “not-known vector” flaviviruses and...

詳細記述

書誌詳細

出版年:	J Virol
主要な著者:	Charlier, Nathalie, Molenkamp, Richard, Leyssen, Pieter, Paeshuyse, Jan, Drosten, Christian, Panning, Marcus, Clercq, Erik De, Bredenbeek, Peter J., Neyts, Johan
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 2004
主題:	Pathogenesis and Immunity
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434118/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15220415/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.14.7418-7426.2004
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