Eukaryotic Initiation Factors 4G and 4A Mediate Conformational Changes Downstream of the Initiation Codon of the Encephalomyocarditis Virus Internal Ribosomal Entry Site

Initiation of translation of encephalomyocarditis virus mRNA is mediated by an internal ribosome entry site (IRES) comprising structural domains H, I, J-K, and L immediately upstream of the initiation codon AUG at nucleotide 834 (AUG(834)). Assembly of 48S ribosomal complexes on the IRES requires eu...

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Detalhes bibliográficos
Main Authors: Kolupaeva, Victoria G., Lomakin, Ivan B., Pestova, Tatyana V., Hellen, Christopher U. T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151537/
https://ncbi.nlm.nih.gov/pubmed/12509466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.2.687-698.2003
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