Eukaryotic Initiation Factors 4G and 4A Mediate Conformational Changes Downstream of the Initiation Codon of the Encephalomyocarditis Virus Internal Ribosomal Entry Site

Initiation of translation of encephalomyocarditis virus mRNA is mediated by an internal ribosome entry site (IRES) comprising structural domains H, I, J-K, and L immediately upstream of the initiation codon AUG at nucleotide 834 (AUG(834)). Assembly of 48S ribosomal complexes on the IRES requires eu...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Kolupaeva, Victoria G., Lomakin, Ivan B., Pestova, Tatyana V., Hellen, Christopher U. T.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2003
Assuntos:	Gene Expression
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151537/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12509466/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.2.687-698.2003
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