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Tumor necrosis factor-related apoptosis-inducing ligand induces neuronal death in a murine model of HIV central nervous system infection

HIV-1 infection in the brain induces neuronal apoptosis leading to HIV-associated dementia. To explore the underlying mechanism, we developed a murine model by using human peripheral blood mononuclear cell (PBMC)–transplanted nonobese diabetic (NOD)–severe combined immunodeficiency (SCID) (hu-PBMC-N...

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Detalhes bibliográficos
Main Authors: Miura, Yoshiharu, Misawa, Naoko, Kawano, Yuji, Okada, Hiroshi, Inagaki, Yoshio, Yamamoto, Naoki, Ito, Mamoru, Yagita, Hideo, Okumura, Ko, Mizusawa, Hidehiro, Koyanagi, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151417/
https://ncbi.nlm.nih.gov/pubmed/12601160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2628048100
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