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Notch1-mediated Signaling Induces MHC Class II Expression through Activation of Class II Transactivator Promoter III in Mast Cells

Mast cells constitutively express Notch1 and Notch2 on the cell surface. Notch ligand Dll1 (Delta-like 1) stimulation induces MHC class II expression in mast cells and renders them as antigen-presenting cells. However, nothing is known about the mechanism by which Notch signaling induces MHC class I...

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Detalhes bibliográficos
Main Authors: Nakano, Nobuhiro, Nishiyama, Chiharu, Yagita, Hideo, Koyanagi, Akemi, Ogawa, Hideoki, Okumura, Ko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069407/
https://ncbi.nlm.nih.gov/pubmed/21321116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.138966
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