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The effect of PU.1 knockdown on gene expression and function of mast cells

PU.1 is a hematopoietic cell-specific transcription factor. In the current study, we investigated the role of PU.1 in the gene expression and the function of mouse mast cells (MCs) in vitro and in vivo. When PU.1 siRNA was introduced into bone marrow-derived MCs (BMMCs), IgE-mediated activation was...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Oda, Yoshihito, Kasakura, Kazumi, Fujigaki, Izumi, Kageyama, Azusa, Okumura, Ko, Ogawa, Hideoki, Yashiro, Takuya, Nishiyama, Chiharu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792452/
https://ncbi.nlm.nih.gov/pubmed/29386516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19378-y
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