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PU.1 Suppresses Th2 Cytokine Expression via Silencing of GATA3 Transcription in Dendritic Cells

The transcription factor PU.1 is predominantly expressed in dendritic cells (DCs) and is essential for DC differentiation. Although there are several reports that PU.1 positively regulates the expression of DC-specific genes, whether PU.1 also has a suppressive effect on DCs is largely unknown. Here...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yashiro, Takuya, Kubo, Masato, Ogawa, Hideoki, Okumura, Ko, Nishiyama, Chiharu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567381/
https://ncbi.nlm.nih.gov/pubmed/26361334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137699
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