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Degradation, Promoter Recruitment and Transactivation Mediated by the Extreme N-Terminus of MHC Class II Transactivator CIITA Isoform III

Multiple relationships between ubiquitin-proteasome mediated protein turnover and transcriptional activation have been well documented, but the underlying mechanisms are still poorly understood. One way to induce degradation is via ubiquitination of the N-terminal α-amino group of proteins. The majo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Beaulieu, Yves B., Leon Machado, Jorge A., Ethier, Sylvain, Gaudreau, Luc, Steimle, Viktor
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752451/
https://ncbi.nlm.nih.gov/pubmed/26871568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148753
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