Critical Contribution of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (Trail) to Apoptosis of Human Cd4(+)T Cells in HIV-1–Infected Hu-Pbl-Nod-Scid Mice

Apoptosis is a key for CD4(+) T cell destruction in HIV-1–infected patients. In this study, human peripheral blood lymphocyte (PBL)-transplanted nonobese diabetic (NOD)-severe combined immunodeficient (SCID) (hu-PBL-NOD-SCID) mice were used to examine in vivo apoptosis after HIV-1 infection. As the...

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Detalhes bibliográficos
Main Authors: Miura, Yoshiharu, Misawa, Naoko, Maeda, Naoyoshi, Inagaki, Yoshio, Tanaka, Yuetsu, Ito, Mamoru, Kayagaki, Nobuhiko, Yamamoto, Naoki, Yagita, Hideo, Mizusawa, Hidehiro, Koyanagi, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193390/
https://ncbi.nlm.nih.gov/pubmed/11238596
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