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Intratumoral IL-12 Gene Therapy Inhibits Tumor Growth In A HCC-Hu-PBL-NOD/SCID Murine Model

PURPOSE: This study aimed to evaluate the efficacy and safety of intratumoral IL-12 gene therapy in an HCC-hu-PBL-NOD/SCID mouse model. MATERIALS AND METHODS: The HCC murine model was generated in NOD/SCID mice, and mice with grafted tumors were injected intraperitoneally with 2 × 10(7) human periph...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Zhou, Zhi-Feng, Peng, Feng, Li, Jie-Yu, Ye, Yun-Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760038/
https://ncbi.nlm.nih.gov/pubmed/31571927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S222097
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