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Anti-SCID mouse reactivity shapes the human CD4+ T cell repertoire in hu-PBL-SCID chimeras

Injecting human peripheral blood mononuclear cells into severe combined immunodeficient (SCID) mice results in long-term engraftment of human lymphocytes, of which > 98% are phenotypically mature, activated T cells. Here we have characterized the human T cells that populate such hu-PBL-SCID chime...

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Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1994
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191753/
https://ncbi.nlm.nih.gov/pubmed/7964463
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