Role of interleukin-4 in human immunoglobulin E formation in hu-PBL-SCID mice.

We studied the role of IL-4 in human IgE formation in severe combined immunodeficient mice engrafted with peripheral blood mononuclear leukocytes (hu-PBL-SCID). PBL from four nonatopic donors produced only small (< 20 ng/ml) or undetectable amounts of IgE in SCID mice whereas engrafted PBL from s...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Spiegelberg, H L, Beck, L, Kocher, H P, Fanslow, W C, Lucas, A H
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1994
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC293907/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8113405/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117024
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