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In Vivo Inhibition of Anti-Hepatitis B Virus Core Antigen (HBcAg) Immunoglobulin G Production by HBcAg-Specific CD4(+) Th1-Type T-Cell Clones in a hu-PBL-NOD/SCID Mouse Model

Hepatitis B virus (HBV) core antigen (HBcAg)-specific CD4(+) T-cell responses are believed to play an important role in the control of human HBV infection. In the present study, HBcAg-specific, HLA-DR13*-restricted CD4(+) Th1-type T-cell clones were generated which secreted both gamma interferon and...

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Udgivet i:J Virol
Principais autores: Cao, Tinghua, Meuleman, Philip, Desombere, Isabelle, Sällberg, Matti, Leroux-Roels, Geert
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114731/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11689626/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.23.11449-11456.2001
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