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In Vivo Inhibition of Anti-Hepatitis B Virus Core Antigen (HBcAg) Immunoglobulin G Production by HBcAg-Specific CD4(+) Th1-Type T-Cell Clones in a hu-PBL-NOD/SCID Mouse Model

Hepatitis B virus (HBV) core antigen (HBcAg)-specific CD4(+) T-cell responses are believed to play an important role in the control of human HBV infection. In the present study, HBcAg-specific, HLA-DR13*-restricted CD4(+) Th1-type T-cell clones were generated which secreted both gamma interferon and...

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Detalhes bibliográficos
Main Authors: Cao, Tinghua, Meuleman, Philip, Desombere, Isabelle, Sällberg, Matti, Leroux-Roels, Geert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114731/
https://ncbi.nlm.nih.gov/pubmed/11689626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.23.11449-11456.2001
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