Biochemical and functional characterization of xenoreactive natural antibodies in hu-PBL-SCID mice.

An in vivo model system to understand the mechanism of xenograft rejection was established using human peripheral blood leukocyte-reconstituted SCID (hu-PBL-SCID) mice. Human xenoreactive natural antibodies (XNA), of IgM and IgG subtypes, capable of binding to pig aortic endothelial cells (PAEC) wer...

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Bibliographic Details
Main Authors: Naziruddin, B, Shiroki, R, Shishido, S, Howard, T, Mohanakumar, T
Format: Artigo
Language:Inglês
Published: 1996
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC507180/
https://ncbi.nlm.nih.gov/pubmed/8636439
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