A triple-mutated allele of granzyme B incapable of inducing apoptosis

Granzyme B (GzmB) is a serine protease involved in many pathologies, including viral infections, autoimmunity, transplant rejection, and antitumor immunity. To measure the extent of genetic variation in GzmB, we screened the GzmB gene for polymorphisms and defined a frequently represented triple-mut...

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Bibliografische gegevens
Hoofdauteurs: McIlroy, Dorian, Cartron, Pierre-François, Tuffery, Pierre, Dudoit, Yasmine, Samri, Assia, Autran, Brigitte, Vallette, François M., Debré, Patrice, Theodorou, Ioannis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2003
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC151380/
https://ncbi.nlm.nih.gov/pubmed/12594335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0437935100
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