A triple-mutated allele of granzyme B incapable of inducing apoptosis

Granzyme B (GzmB) is a serine protease involved in many pathologies, including viral infections, autoimmunity, transplant rejection, and antitumor immunity. To measure the extent of genetic variation in GzmB, we screened the GzmB gene for polymorphisms and defined a frequently represented triple-mut...

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Detalhes bibliográficos
Main Authors: McIlroy, Dorian, Cartron, Pierre-François, Tuffery, Pierre, Dudoit, Yasmine, Samri, Assia, Autran, Brigitte, Vallette, François M., Debré, Patrice, Theodorou, Ioannis
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151380/
https://ncbi.nlm.nih.gov/pubmed/12594335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0437935100
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