A triple-mutated allele of granzyme B incapable of inducing apoptosis

Granzyme B (GzmB) is a serine protease involved in many pathologies, including viral infections, autoimmunity, transplant rejection, and antitumor immunity. To measure the extent of genetic variation in GzmB, we screened the GzmB gene for polymorphisms and defined a frequently represented triple-mut...

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Main Authors: McIlroy, Dorian, Cartron, Pierre-François, Tuffery, Pierre, Dudoit, Yasmine, Samri, Assia, Autran, Brigitte, Vallette, François M., Debré, Patrice, Theodorou, Ioannis
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 2003
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC151380/
https://ncbi.nlm.nih.gov/pubmed/12594335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0437935100
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