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A triple-mutated allele of granzyme B incapable of inducing apoptosis

Granzyme B (GzmB) is a serine protease involved in many pathologies, including viral infections, autoimmunity, transplant rejection, and antitumor immunity. To measure the extent of genetic variation in GzmB, we screened the GzmB gene for polymorphisms and defined a frequently represented triple-mut...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: McIlroy, Dorian, Cartron, Pierre-François, Tuffery, Pierre, Dudoit, Yasmine, Samri, Assia, Autran, Brigitte, Vallette, François M., Debré, Patrice, Theodorou, Ioannis
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151380/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12594335/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0437935100
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