A triple-mutated allele of granzyme B incapable of inducing apoptosis
Granzyme B (GzmB) is a serine protease involved in many pathologies, including viral infections, autoimmunity, transplant rejection, and antitumor immunity. To measure the extent of genetic variation in GzmB, we screened the GzmB gene for polymorphisms and defined a frequently represented triple-mut...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2003
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151380/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12594335/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0437935100 |
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