A triple-mutated allele of granzyme B incapable of inducing apoptosis

Granzyme B (GzmB) is a serine protease involved in many pathologies, including viral infections, autoimmunity, transplant rejection, and antitumor immunity. To measure the extent of genetic variation in GzmB, we screened the GzmB gene for polymorphisms and defined a frequently represented triple-mut...

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Bibliografiske detaljer
Main Authors: McIlroy, Dorian, Cartron, Pierre-François, Tuffery, Pierre, Dudoit, Yasmine, Samri, Assia, Autran, Brigitte, Vallette, François M., Debré, Patrice, Theodorou, Ioannis
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC151380/
https://ncbi.nlm.nih.gov/pubmed/12594335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0437935100
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