Atrial natriuretic peptide and oxytocin induce natriuresis by release of cGMP

Our hypothesis is that oxytocin (OT) causes natriuresis by activation of renal NO synthase that releases NO followed by cGMP that mediates the natriuresis. To test this hypothesis, an inhibitor of NO synthase, l-nitroarginine methyl ester (NAME), was injected into male rats. Blockade of NO release b...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Soares, T. J., Coimbra, T. M., Martins, A. R., Pereira, A. G. F., Carnio, E. C., Branco, L. G. S., Albuquerque-Araujo, W. I. C., de Nucci, G., Favaretto, A. L. V., Gutkowska, J., McCann, S. M., Antunes-Rodrigues, J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1999
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15130/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9874809/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.1.278
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