PTEN overexpression suppresses proliferation and differentiation and enhances apoptosis of the mouse mammary epithelium

The phosphatase PTEN regulates growth, adhesion, and apoptosis, among many other cell processes. To investigate its role during mouse mammary gland development, we generated MK-PTEN, a transgenic mouse model in which human PTEN is overexpressed in ductal and alveolar mammary epithelium during pubert...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	J Clin Invest
Päätekijät:	Dupont, Joëlle, Renou, Jean Pierre, Shani, Moshe, Hennighausen, Lothar, LeRoith, Derek
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Clinical Investigation 2002
Aiheet:	Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151121/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12235113/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI13829
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