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Nuclear endpoint of Wnt signaling: Neoplastic transformation induced by transactivating lymphoid-enhancing factor 1
The interaction between β-catenin and LEF-1/TCF transcription factors plays a pivotal role in the Wnt-1 signaling pathway. The level of β-catenin is regulated by partner proteins, including glycogen synthase kinase-3β (GSK-3β) and the adenomatous polyposis coli (APC) tumor suppressor protein. Geneti...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The National Academy of Sciences
1999
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC15106/ https://ncbi.nlm.nih.gov/pubmed/9874785 |
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