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Nuclear endpoint of Wnt signaling: Neoplastic transformation induced by transactivating lymphoid-enhancing factor 1
The interaction between β-catenin and LEF-1/TCF transcription factors plays a pivotal role in the Wnt-1 signaling pathway. The level of β-catenin is regulated by partner proteins, including glycogen synthase kinase-3β (GSK-3β) and the adenomatous polyposis coli (APC) tumor suppressor protein. Geneti...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The National Academy of Sciences
1999
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC15106/ https://ncbi.nlm.nih.gov/pubmed/9874785 |
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