Curbing the nuclear activities of β-catenin: Control over Wnt target gene expression

Tekijä Hecht, Andreas, Kemler, Rolf
Julkaistu 2000

Differential Control of Wnt Target Genes Involves Epigenetic Mechanisms and Selective Promoter Occupancy by T-Cell Factors

Tekijä Wöhrle, Simon, Wallmen, Britta, Hecht, Andreas
Julkaistu 2007

Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/β-catenin target gene expression

Tekijä Wallmen, Britta, Schrempp, Monika, Hecht, Andreas
Julkaistu 2012

Modeling Wnt/β-Catenin Target Gene Expression in APC and Wnt Gradients Under Wild Type and Mutant Conditions

Tekijä Benary, Uwe, Kofahl, Bente, Hecht, Andreas, Wolf, Jana
Julkaistu 2013

Nuclear endpoint of Wnt signaling: Neoplastic transformation induced by transactivating lymphoid-enhancing factor 1

Tekijä Aoki, Masahiro, Hecht, Andreas, Kruse, Ulrich, Kemler, Rolf, Vogt, Peter K.
Julkaistu 1999

The p300/CBP acetyltransferases function as transcriptional coactivators of β-catenin in vertebrates

Tekijä Hecht, Andreas, Vleminckx, Kris, Stemmler, Marc P., van Roy, Frans, Kemler, Rolf
Julkaistu 2000

Canonical BMP Signaling Executes Epithelial-Mesenchymal Transition Downstream of SNAIL1

Tekijä Frey, Patrick, Devisme, Antoine, Schrempp, Monika, Andrieux, Geoffroy, Boerries, Melanie, Hecht, Andreas
Julkaisussa Cancers (Basel) (2020)

Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/β-catenin targets

Tekijä Weise, Andreas, Bruser, Katja, Elfert, Susanne, Wallmen, Britta, Wittel, Yvonne, Wöhrle, Simon, Hecht, Andreas
Julkaistu 2010

Snapshots of Protein Dynamics and Post-translational Modifications In One Experiment—β-Catenin and Its Functions

Tekijä Luckert, Katrin, Götschel, Frank, Sorger, Peter K., Hecht, Andreas, Joos, Thomas O., Pötz, Oliver
Julkaistu 2011

SNAIL1-mediated downregulation of FOXA proteins facilitates the inactivation of transcriptional enhancer elements at key epithelial genes in colorectal cancer cells

Tekijä Jägle, Sabine, Busch, Hauke, Freihen, Vivien, Beyes, Sven, Schrempp, Monika, Boerries, Melanie, Hecht, Andreas
Julkaisussa PLoS Genet (2017)

Acetylation of Human TCF4 (TCF7L2) Proteins Attenuates Inhibition by the HBP1 Repressor and Induces a Conformational Change in the TCF4::DNA Complex

Tekijä Elfert, Susanne, Weise, Andreas, Bruser, Katja, Biniossek, Martin L., Jägle, Sabine, Senghaas, Niklas, Hecht, Andreas
Julkaistu 2013

The Microphthalmia-Associated Transcription Factor Mitf Interacts with β-Catenin To Determine Target Gene Expression

Tekijä Schepsky, Alexander, Bruser, Katja, Gunnarsson, Gunnar J., Goodall, Jane, Hallsson, Jón H., Goding, Colin R., Steingrimsson, Eirikur, Hecht, Andreas
Julkaistu 2006

Loss of the nuclear Wnt pathway effector TCF7L2 promotes migration and invasion of human colorectal cancer cells

Tekijä Wenzel, Janna, Rose, Katja, Haghighi, Elham Bavafaye, Lamprecht, Constanze, Rauen, Gilles, Freihen, Vivien, Kesselring, Rebecca, Boerries, Melanie, Hecht, Andreas
Julkaisussa Oncogene (2020)

4-Aminoethylamino-emodin – a novel potent inhibitor of GSK-3β– acts as an insulin-sensitizer avoiding downstream effects of activated β-catenin

Tekijä Gebhardt, Rolf, Lerche, Katja S, Götschel, Frank, Günther, Robert, Kolander, Jens, Teich, Lars, Zellmer, Sebastian, Hofmann, Hans-Jörg, Eger, Kurt, Hecht, Andreas, Gaunitz, Frank
Julkaistu 2010

SNAIL1 combines competitive displacement of ASCL2 and epigenetic mechanisms to rapidly silence the EPHB3 tumor suppressor in colorectal cancer

Tekijä Rönsch, Kerstin, Jägle, Sabine, Rose, Katja, Seidl, Maximilian, Baumgartner, Francis, Freihen, Vivien, Yousaf, Afsheen, Metzger, Eric, Lassmann, Silke, Schüle, Roland, Zeiser, Robert, Michoel, Tom, Hecht, Andreas
Julkaisussa Mol Oncol (2014)

Silencing of the EPHB3 tumor-suppressor gene in human colorectal cancer through decommissioning of a transcriptional enhancer

Tekijä Jägle, Sabine, Rönsch, Kerstin, Timme, Sylvia, Andrlová, Hana, Bertrand, Miriam, Jäger, Marcel, Proske, Amelie, Schrempp, Monika, Yousaf, Afsheen, Michoel, Tom, Zeiser, Robert, Werner, Martin, Lassmann, Silke, Hecht, Andreas
Julkaistu 2014