Elucidation of the thromboregulatory role of CD39/ectoapyrase in the ischemic brain

Endothelial CD39 metabolizes ADP released from activated platelets. Recombinant soluble human CD39 (solCD39) potently inhibited ex vivo platelet aggregation in response to ADP and reduced cerebral infarct volumes in mice following transient middle cerebral artery occlusion, even when given 3 hours a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pinsky, David J., Broekman, M. Johan, Peschon, Jacques J., Stocking, Kim L., Fujita, Tomoyuki, Ramasamy, Ravichandran, Connolly, E. Sander, Huang, Judy, Kiss, Szilard, Zhang, Yuan, Choudhri, Tanvir F., McTaggart, Ryan A., Liao, Hui, Drosopoulos, Joan H.F., Price, Virginia L., Marcus, Aaron J., Maliszewski, Charles R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150939/
https://ncbi.nlm.nih.gov/pubmed/11956240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI10649
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados