Inhibition of platelet function by recombinant soluble ecto-ADPase/CD39.

Excessive platelet accumulation and recruitment, leading to vessel occlusion at sites of vascular injury, present major therapeutic challenges in cardiovascular medicine. Endothelial cell CD39, an ecto-enzyme with ADPase and ATPase activities, rapidly metabolizes ATP and ADP released from activated...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Gayle, R B, Maliszewski, C R, Gimpel, S D, Schoenborn, M A, Caspary, R G, Richards, C, Brasel, K, Price, V, Drosopoulos, J H, Islam, N, Alyonycheva, T N, Broekman, M J, Marcus, A J
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1998
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508770/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9576748/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI1753
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