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Inhibition of platelet function by recombinant soluble ecto-ADPase/CD39.
Excessive platelet accumulation and recruitment, leading to vessel occlusion at sites of vascular injury, present major therapeutic challenges in cardiovascular medicine. Endothelial cell CD39, an ecto-enzyme with ADPase and ATPase activities, rapidly metabolizes ATP and ADP released from activated...
Gardado en:
| Publicado en: | J Clin Invest |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
1998
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508770/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9576748/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI1753 |
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