Inhibition of platelet function by recombinant soluble ecto-ADPase/CD39.

Excessive platelet accumulation and recruitment, leading to vessel occlusion at sites of vascular injury, present major therapeutic challenges in cardiovascular medicine. Endothelial cell CD39, an ecto-enzyme with ADPase and ATPase activities, rapidly metabolizes ATP and ADP released from activated...

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Dettagli Bibliografici
Autori principali: Gayle, R B, Maliszewski, C R, Gimpel, S D, Schoenborn, M A, Caspary, R G, Richards, C, Brasel, K, Price, V, Drosopoulos, J H, Islam, N, Alyonycheva, T N, Broekman, M J, Marcus, A J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1998
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC508770/
https://ncbi.nlm.nih.gov/pubmed/9576748
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