Inhibition of platelet function by recombinant soluble ecto-ADPase/CD39.

Excessive platelet accumulation and recruitment, leading to vessel occlusion at sites of vascular injury, present major therapeutic challenges in cardiovascular medicine. Endothelial cell CD39, an ecto-enzyme with ADPase and ATPase activities, rapidly metabolizes ATP and ADP released from activated...

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Bibliografiske detaljer
Udgivet i:	J Clin Invest
Main Authors:	Gayle, R B, Maliszewski, C R, Gimpel, S D, Schoenborn, M A, Caspary, R G, Richards, C, Brasel, K, Price, V, Drosopoulos, J H, Islam, N, Alyonycheva, T N, Broekman, M J, Marcus, A J
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1998
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508770/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9576748/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI1753
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Inhibition of platelet function by recombinant soluble ecto-ADPase/CD39.

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