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Inhibition of platelet function by an aspirin-insensitive endothelial cell ADPase. Thromboregulation by endothelial cells.

We previously reported that platelets become unresponsive to agonists when stimulated in combined suspension with aspirin-treated human umbilical vein endothelial cells. Inhibition occurred concomitant with metabolism of platelet-derived endoperoxides to prostacyclin by endothelial cells. We now dem...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Marcus, A J, Safier, L B, Hajjar, K A, Ullman, H L, Islam, N, Broekman, M J, Eiroa, A M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295705/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1939654/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115485
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