Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite

Nitric oxide (NO) is produced by NO synthase (NOS) in many cells and plays important roles in the neuronal, muscular, cardiovascular, and immune systems. In various disease conditions, all three types of NOS (neuronal, inducible, and endothelial) are reported to generate oxidants through unknown mec...

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Pubblicato in:	J Clin Invest
Autori principali:	Zou, Ming-Hui, Shi, Chaomei, Cohen, Richard A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 2002
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150913/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11901190/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14442
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