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Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite

Nitric oxide (NO) is produced by NO synthase (NOS) in many cells and plays important roles in the neuronal, muscular, cardiovascular, and immune systems. In various disease conditions, all three types of NOS (neuronal, inducible, and endothelial) are reported to generate oxidants through unknown mec...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Zou, Ming-Hui, Shi, Chaomei, Cohen, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150913/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11901190/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14442
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