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Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite

Nitric oxide (NO) is produced by NO synthase (NOS) in many cells and plays important roles in the neuronal, muscular, cardiovascular, and immune systems. In various disease conditions, all three types of NOS (neuronal, inducible, and endothelial) are reported to generate oxidants through unknown mec...

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Hlavní autoři: Zou, Ming-Hui, Shi, Chaomei, Cohen, Richard A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC150913/
https://ncbi.nlm.nih.gov/pubmed/11901190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14442
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