CCR3 is essential for skin eosinophilia and airway hyperresponsiveness in a murine model of allergic skin inflammation

The CC chemokine receptor 3 (CCR3) is expressed by eosinophils, mast cells, and Th2 cells. We used CCR3(–/–) mice to assess the role of CCR3 in a murine model of allergic skin inflammation induced by repeated epicutaneous sensitization with ovalbumin (OVA), and characterized by eosinophil skin infil...

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Detalhes bibliográficos
Main Authors: Ma, Weilie, Bryce, Paul J., Humbles, Alison A., Laouini, Dhafer, Yalcindag, Ali, Alenius, Harri, Friend, Daniel S., Oettgen, Hans C., Gerard, Craig, Geha, Raif S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150891/
https://ncbi.nlm.nih.gov/pubmed/11877470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14097
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