The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness

CCR3 is a chemokine receptor initially thought specific to eosinophils but subsequently identified on TH2 cell subsets, basophils, mast cells, neural tissue, and some epithelia. Because of the prominent role of these cells in allergic disease, including asthma, we generated mice deficient in CCR3 to...

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Detalhes bibliográficos
Main Authors: Humbles, Alison A., Lu, Bao, Friend, Daniel S., Okinaga, Shoji, Lora, Jose, Al-garawi, Amal, Martin, Thomas R., Gerard, Norma P., Gerard, Craig
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122216/
https://ncbi.nlm.nih.gov/pubmed/11830666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.261462598
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