The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness

CCR3 is a chemokine receptor initially thought specific to eosinophils but subsequently identified on TH2 cell subsets, basophils, mast cells, neural tissue, and some epithelia. Because of the prominent role of these cells in allergic disease, including asthma, we generated mice deficient in CCR3 to...

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Détails bibliographiques
Auteurs principaux: Humbles, Alison A., Lu, Bao, Friend, Daniel S., Okinaga, Shoji, Lora, Jose, Al-garawi, Amal, Martin, Thomas R., Gerard, Norma P., Gerard, Craig
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2002
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC122216/
https://ncbi.nlm.nih.gov/pubmed/11830666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.261462598
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