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Inhibition of pulmonary eosinophilia and airway hyperresponsiveness in allergic mice by rolipram: involvement of endogenously released corticosterone and catecholamines

1. This study investigates the role of adrenal-derived catecholamines and corticosterone on the inhibition by rolipram, a phosphodiesterase (PDE)-4 inhibitor, of pulmonary eosinophilia and airway hyperresponsiveness (AHR) in allergic mice. 2. The following experimental groups were studied in mice se...

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Autors principals: Kung, T T, Crawley, Y, Luo, B, Young, S, Kreutner, W, Chapman, R W
Format: Artigo
Idioma:Inglês
Publicat: 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572069/
https://ncbi.nlm.nih.gov/pubmed/10807686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703308
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