Modulation of airway hyperresponsiveness and eosinophilia by selective histamine and 5-HT receptor antagonists in a mouse model of allergic asthma

1. Since both histamine and 5-hydroxytryptamine (5-HT) can be released by murine mast cells, we investigated the possible role of these autacoids on airway hyperresponsiveness (AHR), eosinophil infiltration and serum-IgE levels in a murine model of allergic asthma. 2. Ovalbumin-sensitized mice were...

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Bibliographic Details
Main Authors: De Bie, J J, Henricks, P A J, Cruikshank, W W, Hofman, G, Jonker, E H, Nijkamp, F P, Van Oosterhout, A J M
Format: Artigo
Language:Inglês
Published: 1998
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565459/
https://ncbi.nlm.nih.gov/pubmed/9692769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701901
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