Calcium-sensing receptor antagonists abrogate airway hyperresponsiveness and inflammation in allergic asthma

Airway hyperresponsiveness and inflammation are fundamental hallmarks of allergic asthma that are accompanied by increases in certain polycations, such as eosinophil cationic protein. Levels of these cations in body fluids correlate with asthma severity. We show that polycations and elevated extrace...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Transl Med
Hlavní autoři: Yarova, Polina L., Stewart, Alecia L., Sathish, Venkatachalem, Britt, Rodney D, Thompson, Michael A., Lowe, Alexander P. P., Freeman, Michelle, Aravamudan, Bharathi, Kita, Hirohito, Brennan, Sarah C., Schepelmann, Martin, Davies, Thomas, Yung, Sun, Cholisoh, Zakky, Kidd, Emma J., Ford, William R., Broadley, Kenneth J., Rietdorf, Katja, Chang, Wenhan, Khayat, Mohd E. Bin, Ward, Donald T., Corrigan, Christopher J., Ward, Jeremy P. T., Kemp, Paul J., Pabelick, Christina M., Prakash, Y. S., Riccardi, Daniela
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725057/
https://ncbi.nlm.nih.gov/pubmed/25904744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa0282
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky