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Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model.

Activation of naive T cells requires at least two signals. In addition to the well characterized interaction of the T cell antigen receptor with the antigen/MHC expressed on an antigen-presenting cell, T cell activation also requires costimulation by a second set of signals. The best characterized c...

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Dettagli Bibliografici
Autori principali: Krinzman, S J, De Sanctis, G T, Cernadas, M, Mark, D, Wang, Y, Listman, J, Kobzik, L, Donovan, C, Nassr, K, Katona, I, Christiani, D C, Perkins, D L, Finn, P W
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC507732/
https://ncbi.nlm.nih.gov/pubmed/8981913
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