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Molecular mechanisms of airway hyperresponsiveness in a murine model of steroid-resistant airway inflammation
IL-13 and IL-17A, produced mainly by Th2 and Th17 cells respectively, have an influential role in asthma pathogenesis. We examined the role of IL-13 and IL-17A in mediating airway hyperresponsiveness (AHR), lung inflammation, and mucus metaplasia in a dual Th2/Th17 model of asthma. IL-13 and/or IL-1...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4724491/ https://ncbi.nlm.nih.gov/pubmed/26729801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501531 |
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